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CD38 Protein, Cynomolgus, Rhesus, Recombinant (His)

产品编号 TMPY-03923

CD38 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is Q5VAN0&F6QEE7.

CD38 Protein, Cynomolgus, Rhesus, Recombinant (His)

产品编号 TMPY-03923

CD38 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is Q5VAN0&F6QEE7.

规格	价格	库存
50 μg	¥ 1,960	In stock
100 μg	¥ 3,480	5日内发货
200 μg	¥ 6,150	5日内发货
500 μg	¥ 13,020	5日内发货

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产品信息

生物活性	Measured by its ability to convert the substrate nicotinamide guanine dinucleotide (NGD+) to cyclic GDPribose. The specific activity is >5000pmols/min/ug.
产品描述	CD38 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is Q5VAN0&F6QEE7.
种属	Cynomolgus,Rhesus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q5VAN0&F6QEE7
别名	CD38 molecule
蛋白构建	A DNA sequence encoding the cynomolgus/rhesus CD38 (Q5VAN0/F6QEE7) (Leu44-Ile301) was expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus CD38 sequences are identical. Predicted N terminal: Leu 44
蛋白纯度	> 95 % as determined by SDS-PAGE. > 95 % as determined by SEC-HPLC.
分子量	31.3 kDa (predicted); 41 kDa (reducing conditions)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.