规格

价格

库存

数量

10 mg

¥ 113

现货

25 mg

¥ 167

现货

50 mg

¥ 228

现货

100 mg

¥ 293

现货

500 mg

¥ 548

现货

1 g

¥ 716

现货

2 g

¥ 1,050

现货

生物活性

产品描述	Levocetirizine Dihydrochloride (Xyzal Dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Acting as an antihistaminic agent, it specifically targets the histamine H1-receptor. Levocetirizine Dihydrochloride is the R-enantiomer of Cetirizine, which gives it a higher affinity for the H1-receptor than the S-enantiomer. Due to this enhanced affinity, Levocetirizine Dihydrochloride is effective in treating allergic rhinitis and chronic idiopathic urticaria.
体内活性	Levocetirizine Dihydrochloride（0.4 mg/kg；口服；雄性斯普拉格-道利大鼠）治疗显示，在斯普拉格-道利大鼠中Cmax、AUC0-t、AUC0-∞ 以及 t1/2 分别为 0.34 μg/mL、3.26 μg h/mL、3.67 μg h/mL 和 2.34 小时[1]。
别名	盐酸左旋西替利嗪, Xyzal Dihydrochloride, (-)-Cetirizine Dihydrochloride

化学信息

分子量	461.81
分子式	C₂₁H₂₇Cl₃N₂O₃
CAS No.	130018-87-0
Smiles	O=C(O)COCCN1CCN([C@@H](C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1.Cl.Cl
密度	no data available
颜色	White
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: 90 mg/mL (194.89 mM), Sonication is recommended.

DMSO: 50 mg/mL (108.27 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.33 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO/H2O