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N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone.

N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥ 6,910 | 35日内发货 |
| 产品描述 | N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone. |
| 分子量 | 343.4 |
| 分子式 | C17H17N3O3S |
| CAS No. | 257892-31-2 |
| Smiles | O=C1NC(=O)C(Cc2ccc(OCCNc3ccccn3)cc2)S1 |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度信息 | DMSO:PBS(pH 7.2) (1:3): 0.5 mg/mL (1.46 mM), Sonication is recommended. DMSO: 34 mg/mL (99.01 mM), Sonication is recommended. DMF: 25 mg/mL (72.8 mM), Sonication is recommended. Ethanol: 1 mg/mL (2.91 mM), Sonication is recommended. |
溶液配制表 | |
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