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Cadherin 17/CDH17 Domain 7 Protein, Human, Recombinant (hFc)

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货号 TMPK-00949

别名 P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864.

Cadherin 17/CDH17 Domain 7 Protein, Human, Recombinant (hFc)

Cadherin 17/CDH17 Domain 7 Protein, Human, Recombinant (hFc)

一键复制产品信息
Rating icon 还可以
货号 TMPK-00949 别名 P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864.

规格价格库存数量
5 μg
¥ 433
6-8日内发货
10 μg
¥ 687
6-8日内发货
20 μg
¥ 1,150
5日内发货
50 μg
¥ 2,280
5日内发货
100 μg
¥ 3,850
5日内发货
200 μg
¥ 6,980
5日内发货
500 μg
¥ 15,400
5日内发货
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产品介绍


生物活性
产品描述
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 38.42 kDa and the accession number is Q12864.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号Q12864
蛋白构建Ala668-Gly777
蛋白纯度
> 95% as determined by Tris-Bis PAGE
蛋白性状Solution
缓冲液Supplied as 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl (pH 8.0).
别名P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量38.42 kDa (predicted). Due to glycosylation, the protein migrates to 48-52 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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