ProTx III

Name: ProTx III
Brand: TargetMol
SKU: TP1969
Rating: 4.5 (1 reviews)

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产品编号 TP1969

Potent Nav1.7 blocker (IC50 = 2.5 nM). Also inhibits Nav1.1, Nav1.2, Nav1.3 and Nav1.6 in the nanomolar range. Exhibits no effects on Cav channels or nAChR at 5 μM. Demonstrates analgesic activity in vivo; antagonizes effects of scorpion-venom toxin OD1 at Nav1.7.

ProTx III

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产品编号 TP1969

规格	价格	库存	数量
10 mg	¥ 20,250	待询

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产品介绍

生物活性

产品描述	Potent Nav1.7 blocker (IC50 = 2.5 nM). Also inhibits Nav1.1, Nav1.2, Nav1.3 and Nav1.6 in the nanomolar range. Exhibits no effects on Cav channels or nAChR at 5 μM. Demonstrates analgesic activity in vivo; antagonizes effects of scorpion-venom toxin OD1 at Nav1.7.

化学信息

分子量	3802.41
分子式	C₁₆₂H₂₄₆N₅₂O₄₃S₆
密度	no data available
Sequence	H-Asp-D-Cys(1)-D-Leu-Lys-D-Phe-Gly-D-Trp-D-Lys-Cys(2)-D-Asn-D-Pro-D-Arg-D-Asn-D-Asp-D-Lys-D-Cys(3)-Cys(1)-D-Ser-Gly-D-Leu-D-Lys-Cys(2)-Gly-D-Ser-D-Asn-His-D-Asn-D-Trp-Cys(3)-D-Lys-D-Leu-D-His-aIle-OH
Sequence Short	DCLKFGWKCNPRNDKCCSGLKCGSNHNWCKLHX

储存&溶解度

存储	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	H2O: 1 mg/mL (0.26 mM), Sonication is recommended.