PCSK9 Protein, Macaca nemestrina, Recombinant (His)

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产品编号 TMPJ-00443

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.

PCSK9 Protein, Macaca nemestrina, Recombinant (His)

一键复制产品信息

产品编号 TMPJ-00443

规格	价格	库存
5 μg	¥ 693	6-8日内发货
10 μg	¥ 1,170	6-8日内发货
20 μg	¥ 1,860	5日内发货
50 μg	¥ 3,470	5日内发货
100 μg	¥ 4,930	5日内发货
200 μg	¥ 7,350	5日内发货
500 μg	¥ 12,100	5日内发货
1 mg	¥ 18,900	5日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.
种属	Macaca nemestrina
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	A8T662
别名	Subtilisin/Kexin-Like Protease PC9,Proprotein Convertase Subtilisin/Kexin Type 9,Proprotein Convertase 9,PCSK9,PC9
氨基酸序列	Gln31-Gln152&Ser153-Gln692
蛋白构建	Gln31-Gln152&Ser153-Gln692
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	16-21&55-77 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 0.1M Arg, 0.1M Glu, 20% glycerol, 0.01% tween20, 5% Trehalose, pH 6.0.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.