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PCSK9 Protein, Macaca nemestrina, Recombinant (His)

PCSK9 Protein, Macaca nemestrina, Recombinant (His)

产品编号 TMPJ-00443
别名: Proprotein Convertase Subtilisin/Kexin Type 9, PCSK9, PC9, Proprotein Convertase 9, Subtilisin/Kexin-Like Protease PC9

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.

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PCSK9 Protein, Macaca nemestrina, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 18,900 5日内发货
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产品目录号及名称: PCSK9 Protein, Macaca nemestrina, Recombinant (His) (TMPJ-00443)
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产品描述 Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.
种属 Macaca nemestrina
表达系统 HEK293 Cells
标签 C-6xHis
蛋白编号 A8T662
别名 Proprotein Convertase Subtilisin/Kexin Type 9, PCSK9, PC9, Proprotein Convertase 9, Subtilisin/Kexin-Like Protease PC9
氨基酸序列 Gln31-Gln152&Ser153-Gln692
蛋白构建 Gln31-Gln152&Ser153-Gln692
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 16-21&55-77 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 0.1M Arg, 0.1M Glu, 20% glycerol, 0.01% tween20, 5% Trehalose, pH 6.0.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.

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Keywords

PCSK9 Protein, Macaca nemestrina, Recombinant (His) PC-9 PCSK-9 Proprotein Convertase Subtilisin/Kexin Type 9 PCSK9 PCSK 9 PC9 Proprotein Convertase 9 PC 9 Subtilisin/Kexin-Like Protease PC9 recombinant recombinant-proteins proteins protein

 

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