Tyrosinase-IN-16

Name: Tyrosinase-IN-16
Brand: TargetMol
SKU: T67939
Price: 108 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.94%

货号 T67939Cas号 126651-85-2

Tyrosinase-IN-16对酪氨酸酶具有抑制作用。

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Tyrosinase-IN-16

一键复制产品信息

很棒

纯度: 99.94%

货号 T67939Cas号 126651-85-2

Tyrosinase-IN-16对酪氨酸酶具有抑制作用。

规格	价格	库存
2 mg	¥ 108	现货
5 mg	¥ 173	现货
10 mg	¥ 279	现货
25 mg	¥ 453	现货
50 mg	¥ 685	现货
100 mg	¥ 1,010	现货
500 mg	¥ 2,530	现货

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COA HPLC HNMR 产品操作手册

产品介绍

Tyrosinase-IN-16 AI Summary

Tyrosinase-IN-16 exhibits a variety of bioactivities across multiple assays. It is an inhibitor of Plasmodium falciparum M18 Aspartyl Aminopeptidase (IC50=24123.0 nM), HSD17B4 (39810.7 nM), ROR gamma transcriptional activity (10000.0 nM), Aldehyde Dehydrogenase 1 (ALDH1A1, 17782.8 nM), Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase, 44668.4 nM), Cathepsin L proteinase (CTSL1, IC50 >59642.0 nM), Influenza NS1 Protein Function (1995.3 nM), 15-human lipoxygenase (12589.3 nM), phosphomannose isomerase (PMI, IC50=14492.0 nM and 6150.0 nM confirmed), 12-human lipoxygenase (14125.4 nM), Plasmodium falciparum M17-Family Leucine Aminopeptidase (M17LAP, IC50=2220.0 nM), HPGD (17782.8 nM), Hydroxyacyl-Coenzyme A Dehydrogenase, Type II (15848.9 nM), JMJD2A-Tudor Domain (19952.6 nM), T. brucei phosphofructokinase (30131.3 nM), Histone Lysine Methyltransferase G9a (1258.9 nM), 15-human lipoxygenase 2 (25118.9 nM), PLK1-PBD (13371.4 nM), and Trypanosoma Brucei (31622.8 nM). It activates mitochondrial fusion with a potency of 11220.2 nM and Methionine sulfoxide reductase A (MsrA) with an EC50 >103886.0 nM. Additionally, it has been identified as a novel general anesthetic and induces genotoxicity in human embryonic kidney cells. It also delays death in the malarial parasite plastid (10417.9 nM), inhibits phosphomannose isomerase in the development of antimalarial drugs targeting AMA1-RON (5972.8 nM), and was identified in various counterscreens and HTS assays, such as for C. difficile toxins (AC50=3540.0 nM and 18420.0 nM). Moreover, it inhibits the interaction between DCN1 and UBC12 (IC50=86.05 nM) and the substrate MIKLFSLKQQKKEEESAGGTK-biotin (IC50=126.99 nM) in assay-specific studies..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Tyrosinase-IN-16 inhibited tyrosinase.

化学信息

分子量	256.12
分子式	C₈H₆BrN₃S
CAS No.	126651-85-2
Smiles	SC1=NN=C(N1)C1=CC=CC(Br)=C1
颜色	White
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 250 mg/mL (976.1 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9044 mL	19.5221 mL	39.0442 mL	195.2210 mL
5 mM	0.7809 mL	3.9044 mL	7.8088 mL	39.0442 mL
10 mM	0.3904 mL	1.9522 mL	3.9044 mL	19.5221 mL
20 mM	0.1952 mL	0.9761 mL	1.9522 mL	9.7610 mL
50 mM	0.0781 mL	0.3904 mL	0.7809 mL	3.9044 mL
100 mM	0.0390 mL	0.1952 mL	0.3904 mL	1.9522 mL