VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 87.80 kDa and the accession number is NP_002011.2.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 3,820 | 5日内发货 | ||
100 μg | ¥ 8,840 | 5日内发货 |
生物活性 | Immobilized Recombinant Human VEGF-C Protein (His Tag) at 2 μg/ml (100 μl/well) can bind Recombinant Human VEGFR3/FLT4 Protein (ECD, AVI & His Tag), Biotinylated, The EC50 is 3-10 ng/mL. |
产品描述 | VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 87.80 kDa and the accession number is NP_002011.2. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-Avi-His |
蛋白编号 | NP_002011.2 |
别名 | PCL, VEGFR-3, LMPH1A, fms related tyrosine kinase 4, FLT-41, FLT41, VEGFR3, FLT-4, VEGF Receptor 3 |
蛋白构建 | The Human VEGFR3/FLT4 (NP_002011.2) (Met1-Ile776) was expressed with a C-terminal Avi tag followed by a His tag. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. |
蛋白纯度 | > 95 % as determined by SDS-PAGE. > 95 % as determined by SEC-HPLC. |
分子量 | 87.80 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated PCL VEGFR-3 LMPH1A fms related tyrosine kinase 4 FLT-41 VEGFR 3 FLT 41 FLT41 VEGFR3 FLT-4 FLT4 VEGF Receptor 3 FLT 4 recombinant recombinant-proteins proteins protein