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IL-1RL2 Protein, Human, Recombinant (hFc)
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货号 TMPY-00364
别名 interleukin 1 receptor like 2, IL-36R, IL1R-rp2, IL-1Rrp2, IL1RRP2
IL-1RL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.6 kDa and the accession number is Q9HB29-1.
其他形式的 “IL-1RL2 Protein, Human, Recombinant (hFc)”:
IL-1RL2 Protein, Human, Recombinant (hFc)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPY-00364 别名 interleukin 1 receptor like 2, IL-36R, IL1R-rp2, IL-1Rrp2, IL1RRP2
IL-1RL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.6 kDa and the accession number is Q9HB29-1.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 293 | 6-8日内发货 | |
| 10 μg | ¥ 477 | 6-8日内发货 | |
| 20 μg | ¥ 768 | 5日内发货 | |
| 50 μg | ¥ 1,530 | 5日内发货 | |
| 100 μg | ¥ 2,970 | 5日内发货 |
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| 产品描述 | IL-1RL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.6 kDa and the accession number is Q9HB29-1. |
| 生物活性 | Immobilized Human IL-1 Rrp-2, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-IL-1 Rrp-2 Antibody, hFc Tag with the EC50 of 20.9 ng/ml determined by ELISA (QC Test).Human IL-1 Rrp-2, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-1F10, His Tag with an affinity constant of 35.38 μM as determined in SPR assay (Biacore T200). |
| 研究背景 | The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-hFc |
| 蛋白编号 | Q9HB29-1 |
| 蛋白构建 | Asp20-Arg335 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | interleukin 1 receptor like 2, IL-36R, IL1R-rp2, IL-1Rrp2, IL1RRP2 |
| 内毒素 | Less than 1EU per μg by the LAL method. |
| 分子量 | 62.6 kDa (Predicted); 75-110 kDa (Due to glycosylation) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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