GAS6 Protein, Human, Recombinant (His)

GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. GAS6 Protein, Human, Recombinant (His) is expressed in HEK293 cells.

规格	价格/CNY		货期	数量
50 μg	￥ 3,260	5日内发货

规格

价格/CNY

货期

数量

50 μg

￥ 3,260

5日内发货

生物活性

1. Loaded Anti-Human Gas6 mAb-Fc on Protein A Biosensor, can bind Human GAS6-His with an affinity constant of 5.45 nM as determined in BLI assay.
2. Immobilized Human AXL-His at 10μg/ml (100 μl/well) can bind Human GAS6-His*: Biotinylated by NHS-biotin prior to testing. The ED50 of Recombinant Human GAS6-His* is 0.04466 ug/ml.

产品描述

种属	Human
表达系统	HEK293
标签	C-His
蛋白编号	Q14393-2
蛋白构建	Recombinant Human Growth Arrest-specific Protein 6 is produced by our Mammalian expression system and the target gene encoding Ala31-Ala678 is expressed with a 6His tag at the C-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE.
分子量	72.7 KDa (Predicted), 80-90 KDa (Reducing conditions)

内毒素	< 1 EU/µg as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

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GAS6 Protein, Human, Recombinant (His)

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