Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 820 | 5日内发货 | ||
50 μg | ¥ 2,480 | 5日内发货 | ||
500 μg | ¥ 12,100 | 5日内发货 | ||
1 mg | ¥ 17,400 | 5日内发货 |
产品描述 | Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification). |
种属 | Human |
表达系统 | Human Cells |
标签 | C-6His |
蛋白编号 | Q9UNW1 |
别名 | 3, 4, 5)-Tetrakisphosphate 3-Phosphatase, 2, 5)P(4) 3-Phosphatase, 3-BPG Phosphatase, Multiple Inositol Polyphosphate Phosphatase 1, 3-Bisphosphoglycerate 3-Phosphatase, MINPP1, Ins(1, Ins(1,3,4,5)P(4) 3-phosphatase, Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase, 2,3-BPG phosphatase, Inositol (1, 2,3-bisphosphoglycerate 3-phosphatase, MIPP |
氨基酸序列 | Ser31-Leu487 |
蛋白构建 | Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Leu487 is expressed with a 6His tag at the C-terminus. |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 56 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
存储 |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
运输方式 |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification). |
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MINPP1 Protein, Human, Recombinant (His) 3 4 5)-Tetrakisphosphate 3-Phosphatase 2 5)P(4) 3-Phosphatase 3-BPG Phosphatase Multiple Inositol Polyphosphate Phosphatase 1 MINPP 1 MINPP-1 3-Bisphosphoglycerate 3-Phosphatase MINPP1 Ins(1 Ins(1,3,4,5)P(4) 3-phosphatase Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase 2,3-BPG phosphatase Inositol (1 2,3-bisphosphoglycerate 3-phosphatase MIPP recombinant recombinant-proteins proteins protein