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IL-4 Protein, Human, Recombinant (hFc)

IL-4 Protein, Human, Recombinant (hFc)

产品编号 TMPJ-00034
别名: Lymphocyte Stimulatory Factor 1, 白介素, BSF-1, Pitrakinra, IL-4, 白细胞介素, IL4, Interleukin-4, Binetrakin, B-Cell Stimulatory Factor 1

IL-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40-55 KDa and the accession number is P05112.

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IL-4 Protein, Human, Recombinant (hFc)
规格 价格/CNY 货期 数量
10 μg ¥ 820 5日内发货
50 μg ¥ 2,480 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: IL-4 Protein, Human, Recombinant (hFc) (TMPJ-00034)
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生物活性
技术参数
产品性质
生物活性 1. Loaded Cynomolgus IL-4RA-His on HIS1K Biosensor, can bind Human IL-4-Fc with an affinity constant of <10-3 nM as determined in BLI assay. (Regularly tested). 2. Immobilized Human IL-4-Fc at 5μg/ml (100 μl/well) can bind Cynomolgus IL-4Ra-His . The ED50 of Recombinant Human IL-4Ra-His is 79.49 ng/ml. (Regularly tested);
产品描述 IL-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40-55 KDa and the accession number is P05112.
种属 Human
表达系统 HEK293 Cells
标签 C-hFc
蛋白编号 P05112
别名 Lymphocyte Stimulatory Factor 1, 白介素, BSF-1, Pitrakinra, IL-4, 白细胞介素, IL4, Interleukin-4, Binetrakin, B-Cell Stimulatory Factor 1
氨基酸序列 His25-Ser153
蛋白构建 His25-Ser153
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
分子量 40-55 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.

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Keywords

IL-4 Protein, Human, Recombinant (hFc) Lymphocyte Stimulatory Factor 1 IL 4 白介素 BSF-1 Pitrakinra IL-4 BSF1 白细胞介素 IL4 Interleukin-4 Binetrakin BSF 1 B-Cell Stimulatory Factor 1 recombinant recombinant-proteins proteins protein

 

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