CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 KDa and the accession number is H0VUB1.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 740 | 5日内发货 | ||
50 μg | ¥ 1,970 | 5日内发货 | ||
500 μg | ¥ 8,860 | 5日内发货 | ||
1 mg | ¥ 12,600 | 5日内发货 |
生物活性 | Immobilized Mouse B7-1-Fc at 5 μg/ml (100 μl/well) can bind Cavia porcellus CTLA-4-His . The ED50 of Recombinant Cavia porcellus CTLA-4-His is 4.29 ng/ml. (Regularly tested) |
产品描述 | CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 KDa and the accession number is H0VUB1. |
种属 | Cavia porcellus |
表达系统 | P. pastoris (Yeast) |
标签 | C-6xHis |
蛋白编号 | H0VUB1 |
别名 | Cytotoxic T-lymphocyte protein 4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4, CD152, CTLA-4 |
氨基酸序列 | Ala37-Asp161 |
蛋白构建 | Ala37-Asp161 |
蛋白纯度 | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 18-40 KDa (reducing condition) |
内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. |
存储 |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4. |
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CTLA-4 Protein, Cavia porcellus, Recombinant (His) Cytotoxic T-lymphocyte protein 4 CTLA4 Cytotoxic T-lymphocyte-associated antigen 4 CD-152 CD152 CTLA 4 CTLA-4 CD 152 recombinant recombinant-proteins proteins protein