Ro15-4513 usually acts as a partial inverse agonist at GABAA receptors [3].

Ro 15-4513 (i.p.; 3?mg/kg; 15?min before administration of 1.5?g/kg ethanol) reverses ethanol-induced sedation in GABAA receptor δ subunit-deficient mice. Ro 15-4513 (i.p.; 3?mg/kg; 10?min before being tested) fully inhibits the ethanol-induced (1.8?g/kg) reduction in total locomotor activity and partly the reduction in rearing [2].