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Anti-CEACAM6 Antibody (9H394)

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产品编号 TMAY-01219
别名 NCA, CEAL, CEA, CD66c, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)

Anti-CEACAM6 Antibody (9H394) 是一种 Mouse 抗体,靶向 CEACAM6。Anti-CEACAM6 Antibody (9H394) 可用于 ELISA,FCM。

Anti-CEACAM6 Antibody (9H394)

Anti-CEACAM6 Antibody (9H394)

Rating icon 还可以
产品编号 TMAY-01219 别名 NCA, CEAL, CEA, CD66c, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)

Anti-CEACAM6 Antibody (9H394) 是一种 Mouse 抗体,靶向 CEACAM6。Anti-CEACAM6 Antibody (9H394) 可用于 ELISA,FCM。

规格价格库存数量
20 μL
¥ 790
5日内发货
100 μL
¥ 1,684
5日内发货
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产品介绍

生物活性
产品描述
Anti-CEACAM6 Antibody (9H394) is a Mouse antibody targeting CEACAM6. Anti-CEACAM6 Antibody (9H394) can be used in ELISA,FCM.
别名NCA, CEAL, CEA, CD66c, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
Ig Type
Monoclonal Mouse IgG1
克隆号
9H394
交叉反应
Human
验证活性
Flow cytometric analysis of Human CEACAM6 expression on human whole blood granulocytes. Cells were stained with purified anti-Human CEACAM6, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
应用
ELISA,FCM
推荐剂量
ELISA: 1:1000-1:2000; FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM6 / CD66c (rhCEACAM6; TMPY-00971; NP_002474.4; Met 1-Gly 320). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
PE
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human CD66c protein (TMPY-00971)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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