EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled

The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.6 kDa and the accession number is NP_001333870.1.

规格	价格/CNY		数量
100 μg	￥ 8,900	5日内发货
500 μg	￥ 23,700	5日内发货
1 mg	￥ 39,500	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 8,900

5日内发货

500 μg

￥ 23,700

5日内发货

1 mg

￥ 39,500

5日内发货

产品描述

种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	NP_001333870.1
别名	EC 2.7.10.1, EC 2.7.10, ERBB1, EGFR, mENA, NISBD2, HER1, ErbB, PIG61, LEGFR
蛋白构建	Leu25-Ser378
分子量	41.6 kDa (predicted)

内毒素	< 1 EU/μg by the LAL method.
缓冲液	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
存储	It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 6 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.