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Erythrosin B

Name: Erythrosin B
Brand: TargetMol
SKU: T0578
Price: 143 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 98.77%

货号 T0578Cas号 15905-32-5

别名 藻红B, Tetraiodofluorescein, Iodeosin

Erythrosin B (Iodeosin) 是一种四碘荧光素，在某些食物（樱桃、鱼）中用作红色色素，用作某些细胞类型的染色剂，以及用作牙菌斑的披露物。其分子结构与甲状腺素相似。

Erythrosin B

一键复制产品信息

很棒

纯度: 98.77%

货号 T0578 别名 藻红B, Tetraiodofluorescein, IodeosinCas号 15905-32-5

规格	价格	库存
5 mg	¥ 143	现货
10 mg	¥ 195	现货
25 mg	¥ 297	现货
50 mg	¥ 388	现货
100 mg	¥ 698	现货
500 mg	¥ 1,120	现货
1 g	¥ 1,330	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 98.77%

颜色: 红色

性状: Solid

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资源下载:

COA HNMR LCMS 产品操作手册

产品介绍

Erythrosin B AI Summary

Erythrosin B exhibits multifaceted bioactivities, including inhibition of several enzymes and proteins such as Ubiquitin-specific Protease USP2a, Menin-MLL interaction, Thyroid Hormone Receptor, Steroid Receptor Coregulator 2, RecQ-Like DNA Helicase 1, Tyrosyl-DNA Phosphodiesterase (TDP1), Schistosoma Mansoni Peroxiredoxins, Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase), Fructose-1,6-bisphosphate Aldolase, L3MBTL1, AmpC Beta-Lactamase, Bloom's syndrome helicase (BLM), GCN5L2, T. brucei phosphofructokinase, Chronic Active B-Cell Receptor Signaling, Eya2, and polymerase Kappa. The compound also modulates lipid storage in Drosophila S3 cells and activates the Relaxin Receptor RXFP1. It shows inhibitory effects on the growth of various human tumor cell lines, including those from renal, non-small cell lung, leukemia, melanoma, colon, prostate, central nervous system, ovarian, and breast cancers. Additionally, Erythrosin B affects protein-protein interactions, particularly between human Fc-conjugated CD40 and FLAG-tagged biotinylated CD40L costimulatory proteins, with a ratio IC50 of 1.04 in the presence of Triton-X 100. The compound inhibits the Zika virus NS2B-NS3 protease with an IC50 of 1700.0 nM and displays an EC50 of 600.0 nM in a cell-based assay. Binding affinity studies via isothermal titration calorimetry reveal that Erythrosin B has a strong affinity to human N-terminal His6-tagged and thrombin cleavage fused BLVRB protein, with a dissociation constant (Kd) around 160.0 nM. The associated thermodynamic parameters include a deltaH of -6.38 kcal/mol, TdeltaS of 2.91 kcal/mol, and deltaG of -9.28 kcal/mol. Moreover, Erythrosin B demonstrates antiviral activities against DENV2, Zika virus, and West Nile virus, with respective EC50 values of 1200.0 nM, 620.0 nM, and 660.0 nM in human A549 cells after 48 hours, as measured by plaque reduction assays..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Erythrosin B (Iodeosin) , a tetraiodofluorescein, is used as a red coloring in some foods (cherries, fish), as a stain of some cell types, and as a disclosure of DENTAL PLAQUE. Its molecular structure is similar to THYROXINE.
别名	藻红B, Tetraiodofluorescein, Iodeosin

化学信息

分子量	835.89
分子式	C₂₀H₈I₄O₅
CAS No.	15905-32-5
Smiles	Oc1c(I)cc2c(Oc3c(I)c(O)c(I)cc3C22OC(=O)c3ccccc23)c1I
密度	2.4391 g/cm3 (Estimated)

储存&溶解度

存储

溶解度信息

DMSO: 50 mg/mL (59.82 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1963 mL	5.9816 mL	11.9633 mL	59.8165 mL
5 mM	0.2393 mL	1.1963 mL	2.3927 mL	11.9633 mL
10 mM	0.1196 mL	0.5982 mL	1.1963 mL	5.9816 mL
20 mM	0.0598 mL	0.2991 mL	0.5982 mL	2.9908 mL
50 mM	0.0239 mL	0.1196 mL	0.2393 mL	1.1963 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

Erythrosin B

Erythrosin B

Erythrosin B

Erythrosin B 相关产品

产品介绍

计算器

体内实验配液计算器

剂量转换

引用文献

关键词