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IL-5 Protein, Human, Recombinant (His)

Synonyms: 白细胞介素, 白介素, TRF, interleukin 5, IL-5, EDF
货号 TMPY-05576 一键复制产品信息 纯度: 97.7%
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IL-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is P05113.

IL-5 Protein, Human, Recombinant (His)

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纯度: 97.7%

货号 TMPY-05576

别名 白细胞介素, 白介素, TRF, interleukin 5, IL-5, EDF

IL-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is P05113.

IL-5 Protein, Human, Recombinant (His)
规格价格库存数量
5 μg
¥ 492
3日内发货
10 μg
¥ 785
3日内发货
20 μg
¥ 1,320
3日内发货
50 μg
¥ 2,620
3日内发货
100 μg
¥ 4,430
现货
200 μg
¥ 7,250
5日内发货
500 μg
¥ 13,870
5日内发货
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纯度: 97.7%
颜色: 白色
性状: Lyophilized powder
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产品介绍


生物活性
产品描述
IL-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is P05113.
生物活性
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.2-1.2 ng/mL.
IL-5 Protein, Human, Recombinant (His)
研究背景
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony-stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues and can modulate eosinophil behavior at every stage from maturation to survival.
种属
Human
表达系统
HEK293 Cells
标签C-His
蛋白编号P05113
蛋白构建A DNA sequence encoding the human IL5 (NP_000870.1) (Met1-Ser134) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ile 20
蛋白纯度
> 95 % as determined by SDS-PAGE.
IL-5 Protein, Human, Recombinant (His)
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
别名白细胞介素, 白介素, TRF, interleukin 5, IL-5, EDF
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量14.6 kDa (predicted)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

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