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来自弧菌的 Cholera toxin B subunit (CTB, from vibrio cholerae) 对细胞无毒,且不具备内在腺苷酸环化酶活性。它通过与神经节苷脂 GM1.8 结合附着于细胞。研究表明,Cholera toxin B subunit 是小胶质细胞的可靠标记物(因为其细胞表面神经节苷脂 GM1 丰富),但不适用于标记少突胶质细胞或星形胶质细胞。Cholera toxin B subunit 也被报告为一种利用免疫组织化学研究轴突运输的极佳示踪剂,并已被广泛用作膜脂筏的标记物。
来自弧菌的 Cholera toxin B subunit (CTB, from vibrio cholerae) 对细胞无毒,且不具备内在腺苷酸环化酶活性。它通过与神经节苷脂 GM1.8 结合附着于细胞。研究表明,Cholera toxin B subunit 是小胶质细胞的可靠标记物(因为其细胞表面神经节苷脂 GM1 丰富),但不适用于标记少突胶质细胞或星形胶质细胞。Cholera toxin B subunit 也被报告为一种利用免疫组织化学研究轴突运输的极佳示踪剂,并已被广泛用作膜脂筏的标记物。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 待询 | 期货 | |
50 mg | 待询 | 期货 |
产品描述 | Cholera toxin B subunit, from Vibrio cholerae (CTB, from vibrio cholerae), is non-toxic to cells and lacks inherent adenylate cyclase activity. It adheres to cells by binding to ganglioside GM1.8. Research indicates that this subunit is an excellent marker for microglia due to their surface richness in ganglioside GM1, though it is not as effective for oligodendrocytes or astrocytes. Additionally, CTB is reported to be an excellent tracer for studying axonal transport using immunohistochemistry and has been widely used as a marker for membrane lipid rafts. |
CAS No. | 131096-89-4 |
存储 | keep away from direct sunlight | store at 4°C |
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
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