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IL-5 Protein, Human, Recombinant (His & Avi)
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货号 TMPK-00021
别名 白细胞介素, 白介素, TRF, T-cell replacing factor, Interleukin-5, IL-5, EDF
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA). IL-5 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 16.1 kDa and the accession number is P05113.
其他形式的 “IL-5 Protein, Human, Recombinant (His & Avi)”:
IL-5 Protein, Human, Recombinant (His & Avi)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPK-00021 别名 白细胞介素, 白介素, TRF, T-cell replacing factor, Interleukin-5, IL-5, EDF
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA). IL-5 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 16.1 kDa and the accession number is P05113.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 373 | 6-8日内发货 | |
| 10 μg | ¥ 598 | 6-8日内发货 | |
| 20 μg | ¥ 983 | 5日内发货 | |
| 50 μg | ¥ 1,930 | 5日内发货 | |
| 100 μg | ¥ 3,250 | 5日内发货 | |
| 200 μg | ¥ 5,890 | 5日内发货 | |
| 500 μg | ¥ 13,000 | 5日内发货 |
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| 产品描述 | IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA). IL-5 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 16.1 kDa and the accession number is P05113. |
| 生物活性 | 1. Immobilized Human IL-5, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-5 R alpha, hFc Tag with the EC50 of 6.9ng/ml determined by ELISA (QC Test).
2. Human IL-5, His Tag immobilized on CM5 Chip can bind Human IL-5Ra, His Tag with an affinity constant of 4.9nM as determined in a SPR assay. |
| 研究背景 | IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA). |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | N-His-Avi |
| 蛋白编号 | P05113 |
| 蛋白构建 | Ile20-Ser134 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | 白细胞介素, 白介素, TRF, T-cell replacing factor, Interleukin-5, IL-5, EDF |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 16.1 kDa (predicted). Due to glycosylation, the protein migrates to 18-25 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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