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CD93/C1qR1 Protein, Mouse, Recombinant (hFc)

产品编号 TMPY-06844

CD93/C1qR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.83 kDa and the accession number is NP_034870.1.

CD93/C1qR1 Protein, Mouse, Recombinant (hFc)

产品编号 TMPY-06844

CD93/C1qR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.83 kDa and the accession number is NP_034870.1.

规格	价格	库存	数量
100 μg	¥ 3,820	现货
1 mg	¥ 24,900	5日内发货

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产品信息

生物活性	Immobilized Recombinant Human IGFBP7 / IBP-7 Protein (His Tag) at 2μg/mL (100μL/well) can bind Recombinant Mouse CD93 Protein (Fc Tag) , the EC50 is 150-450 ng/mL.
产品描述	CD93/C1qR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.83 kDa and the accession number is NP_034870.1.
种属	Mouse
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	NP_034870.1
别名	Ly68,CD93 molecule,C1qrp,C1qr1,AW555904,AA4.1,AA145088,6030404G09Rik
蛋白构建	A DNA sequence encoding the Mouse CD93 (NP_034870.1) (Met1-Asn572) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Ala 23
蛋白纯度	≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
分子量	85.83 kDa (predicted); 134.85 kDa (reducing conditions)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.