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Pleiotrophin/PTN Protein, Mouse, Recombinant (His)
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很棒SPR兼容缓冲液
货号 TMPJ-01051
别名 PTN, Pleiotrophin, Osteoblast-specific factor 1, OSF-1, Heparin-binding growth factor 8, Heparin-binding brain mitogen, HBGF-8, HBBM
Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein,Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, and constitute a family. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated with neuronal development or stresses such as brain ischemia and Parkinson's disease.
其他形式的 “Pleiotrophin/PTN Protein, Mouse, Recombinant (His)”:
Pleiotrophin/PTN Protein, Mouse, Recombinant (His)
一键复制产品信息 很棒SPR兼容缓冲液
货号 TMPJ-01051 别名 PTN, Pleiotrophin, Osteoblast-specific factor 1, OSF-1, Heparin-binding growth factor 8, Heparin-binding brain mitogen, HBGF-8, HBBM
Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein,Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, and constitute a family. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated with neuronal development or stresses such as brain ischemia and Parkinson's disease.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 385 | 现货 | |
| 10 μg | ¥ 620 | 6-8日内发货 | |
| 20 μg | ¥ 958 | 5日内发货 | |
| 50 μg | ¥ 1,730 | 5日内发货 | |
| 100 μg | ¥ 2,780 | 5日内发货 | |
| 200 μg | ¥ 4,550 | 5日内发货 | |
| 500 μg | ¥ 8,700 | 5日内发货 | |
| 1 mg | ¥ 12,600 | 5日内发货 |
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产品介绍
生物活性
化学信息
储存&溶解度
| 产品描述 | Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein,Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, and constitute a family. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated with neuronal development or stresses such as brain ischemia and Parkinson's disease. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein，Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, and constitute a family. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated with neuronal development or stresses such as brain ischemia and Parkinson’s disease. |
| 种属 | Mouse |
| 表达系统 | HEK293 Cells |
| 标签 | C-6xHis |
| 蛋白编号 | P63089 |
| 氨基酸序列 | Gly33-Asp168 |
| 蛋白构建 | Gly33-Asp168 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | PTN, Pleiotrophin, Osteoblast-specific factor 1, OSF-1, Heparin-binding growth factor 8, Heparin-binding brain mitogen, HBGF-8, HBBM |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 18 KDa (reducing condition) |
| 颜色 | White |
| 物理性状 | Lyophilized powder |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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