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Anti-GPHA2 Antibody (7J791)
还可以产品编号 TMAY-02652
别名 ZSIG51, GPA2, glycoprotein hormone α 2, glycoprotein hormone alpha 2, A2
Anti-GPHA2 Antibody (7J791) 是一种 Mouse 抗体，靶向 GPHA2。Anti-GPHA2 Antibody (7J791) 可用于 ELISA。
Anti-GPHA2 Antibody (7J791)
Anti-GPHA2 Antibody (7J791)
还可以产品编号 TMAY-02652 别名 ZSIG51, GPA2, glycoprotein hormone α 2, glycoprotein hormone alpha 2, A2
Anti-GPHA2 Antibody (7J791) 是一种 Mouse 抗体，靶向 GPHA2。Anti-GPHA2 Antibody (7J791) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,694 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-GPHA2 Antibody (7J791) is a Mouse antibody targeting GPHA2. Anti-GPHA2 Antibody (7J791) can be used in ELISA. |
| 别名 | ZSIG51, GPA2, glycoprotein hormone α 2, glycoprotein hormone alpha 2, A2 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7J791 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GPHA2 / glycoprotein hormone alpha 2 (rh GPHA2 / glycoprotein hormone alpha 2; TMPY-03784; Q96T91; Met1-Tyr129). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The alpha-subunit combines with four distinct beta-subunits giving rise to four biologically active hormones in the human: FSH, LH, TSH, and CG. GPHA2 and glycoprotein hormone beta 5 (GPHB5) can form a noncovalent heterodimer. GPHA2 can be detected in a variety of tissues. Recombinant A2/B5 heterodimeric glycoproteins activate human TSH receptors, but not LH and FSH receptors, and shows high affinity to TSH receptors in a radioligand receptor assay. The heterodimer also stimulates cAMP production and thymidine incorporation by cultured thyroid cells and increases serum thyroxine levels in TSH-suppressed rats in vivo. This new heterodimeric glycoprotein hormone was named Thyrostimulin based on its thyroid-stimulating activity. The expression of Thyrostimulin in the anterior pituitary known to express TSH receptors suggested a paracrine mechanism. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human GPHA2 / glycoprotein hormone alpha 2 Protein (TMPY-03784) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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