Proglumide hemicalcium

Name: Proglumide hemicalcium
Brand: TargetMol
SKU: T12544
Rating: 4.5 (1 reviews)

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产品编号 T12544Cas号 85068-56-0

Proglumide hemicalcium is a antagonist of nonpeptide and orally active cholecystokinin (CCK)-A/B receptors, has antiepileptic and antioxidant activities.

Proglumide hemicalcium

还可以

产品编号 T12544Cas号 85068-56-0

Proglumide hemicalcium is a antagonist of nonpeptide and orally active cholecystokinin (CCK)-A/B receptors, has antiepileptic and antioxidant activities.

规格	价格	库存
25 mg	待询	3-6月
50 mg	待询	3-6月
100 mg	待询	3-6月

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产品描述	Proglumide hemicalcium is a antagonist of nonpeptide and orally active cholecystokinin (CCK)-A/B receptors, has antiepileptic and antioxidant activities.
体外活性	in vitro, Proglumide at concentrations between 0.3-10 mM inhibits CCK-stimulated amylase release dose-dependently, while Proglumide does not influence the basal amylase release at concentrations between 0-3 mM. Dose-response curves to CCK for amylase release shifted to the right with increase in Proglumide concentration. This inhibition by Proglumide is reversible. In addition, the effect of Proglumide is selective for CCK and its related peptide[2].
体内活性	Proglumide treatment is significantly effective in ameliorating the seizure activities, cognitive dysfunctions, and cerebral oxidative stress[1].