Name: Mesothelin Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-00132
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 429

3日内发货

10 μg

¥ 695

3日内发货

20 μg

¥ 1,130

3日内发货

50 μg

¥ 2,260

现货

100 μg

¥ 4,010

5日内发货

200 μg

¥ 7,090

5日内发货

500 μg

¥ 15,000

5日内发货

生物活性

产品描述	Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
生物活性	Immobilized Recombinant Human MSLN/Mesothelin Protein (Cat#TMPY-00132) at 2 μg/mL (100 μL/well) can bind Anti-MSLN Antibody, human IgG1, the EC50 is 7.5-24 ng/mL.
研究背景	The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
种属	Human
表达系统	HEK293 Cells
标签	Tag Free
蛋白编号	Q13421-3
蛋白构建	A DNA sequence encoding the human MSLN (NP_005814.2) (Glu296-Gly580) was expressed with two additional amino acids (Gly & Pro) at the N-terminus. Predicted N terminal: Gly
蛋白纯度	≥ 85 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
别名	SMRP, MPF, Mesothelin
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	32.4 kDa (predicted); (reducing condition, due to glycosylation)

储存&溶解度

运输方式	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Mesothelin Protein, Human, Recombinant

Mesothelin Protein, Human, Recombinant

产品介绍

计算器

剂量转换

引用文献

技术支持