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FGF-1 Protein, Cynomolgus, Recombinant

产品编号 TMPY-03477

FGF-1 Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa.

FGF-1 Protein, Cynomolgus, Recombinant

FGF-1 Protein, Cynomolgus, Recombinant

产品编号 TMPY-03477
FGF-1 Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa.
规格价格库存数量
100 μg
¥ 1,950
5日内发货
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常见问题解答
化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别?盐形式和游离态有什么区别?
盐和非盐形式化合物的活性分子是一样的,在生物实验中起到的效果也一致,活性和使用方法都是一样的。只是由于呈盐不同,物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。
如何选择某个靶点的特异性或总的抑制剂?特异性和非特异性的区别是什么?
抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂,对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。 一般评价一个抑制剂的抑制效率主要看 IC50 值,IC50 值越低,说明抑制剂效率越高。建议您根据以上几个特征进行综合选择,也可联系技术帮您推荐相关抑制剂。
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产品信息

生物活性
Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.1-0.4 ng/mL.
产品描述
FGF-1 Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa.
种属
Cynomolgus
表达系统
E. coli
标签Tag Free
别名
fibroblast growth factor 1 (acidic)
蛋白构建
A DNA sequence encoding the cyno FGF1 (Phe16-Asp155) was expressed and purified with an initial Met. Predicted N terminal: Met
蛋白纯度
> 95 % as determined by SDS-PAGE
分子量16 kDa (predicted); 16 kDa (reducing conditions)
内毒素Please contact us for more information.
缓冲液Supplied as sterile PBS, pH 7.4, 20% glycerol.
复溶方法
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储
It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景
aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.References

参考文献

SCI 文献

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

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