购物车
- 全部删除
您的购物车当前为空
Anti-HER3/ERBB3 Antibody (5O888)
还可以产品编号 TMAY-00451
别名 erb-b2 receptor tyrosine kinase 3
Anti-HER3/ERBB3 Antibody (5O888) 是一种 Mouse 抗体，靶向 HER3/ERBB3。Anti-HER3/ERBB3 Antibody (5O888) 可用于 ELISA(Cap)。
Anti-HER3/ERBB3 Antibody (5O888)
Anti-HER3/ERBB3 Antibody (5O888)
还可以产品编号 TMAY-00451 别名 erb-b2 receptor tyrosine kinase 3
Anti-HER3/ERBB3 Antibody (5O888) 是一种 Mouse 抗体，靶向 HER3/ERBB3。Anti-HER3/ERBB3 Antibody (5O888) 可用于 ELISA(Cap)。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 580 | 5日内发货 | |
| 100 μL | ¥ 1,689 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-HER3/ERBB3 Antibody (5O888) is a Mouse antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (5O888) can be used in ELISA(Cap). |
| 别名 | erb-b2 receptor tyrosine kinase 3 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5O888 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunofluorescence staining of Human ErbB3 in MCF7 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human ErbB3 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cell membrane. 2. Flow cytometric analysis of human ErbB3 expression on MCF-7 cells. Cells were stained with purified anti-Human ErbB3, then a FITC-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HER3 / ErbB3 (rh HER3 / ErbB3; TMPY-01389; NP_001973.2; Met1-Thr643). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | PE |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human HER3 / ErbB3 protein (TMPY-01389) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-HER3/ERBB3 Antibody (5O888) | purchase Anti-HER3/ERBB3 Antibody (5O888) | Anti-HER3/ERBB3 Antibody (5O888) cost | order Anti-HER3/ERBB3 Antibody (5O888)
嗨！有任何问题？点我咨询
评论内容