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2-Chloronaphthoquinone

Name: 2-Chloronaphthoquinone
Brand: TargetMol
SKU: T7075
Price: 108 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.98%

货号 T7075Cas号 1010-60-2

别名 2-氯-1,4-萘醌, 2-Chloro-1,4-naphthoquinone

2-Chloronaphthoquinone (2-Chloro-1,4-naphthoquinone) 是一种取代的萘醌，用作杀虫剂和杀螨剂。

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2-Chloronaphthoquinone

一键复制产品信息

很棒

纯度: 99.98%

货号 T7075 别名 2-氯-1,4-萘醌, 2-Chloro-1,4-naphthoquinoneCas号 1010-60-2

2-Chloronaphthoquinone (2-Chloro-1,4-naphthoquinone) 是一种取代的萘醌，用作杀虫剂和杀螨剂。

规格	价格	库存
200 mg	¥ 108	现货
500 mg	¥ 163	现货
1 g	¥ 228	现货
5 g	¥ 463	现货
10 g	¥ 673	现货
25 g	¥ 1,120	现货
50 g	¥ 1,660	现货

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

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纯度: 99.98%

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资源下载:

COA HNMR HPLC 产品操作手册

产品介绍

2-Chloronaphthoquinone AI Summary

2-Chloronaphthoquinone is characterized by moderate lipophilicity, as indicated by partition coefficient values (LogP) ranging from 2.15 to 2.29. It shows a moderate to high capacity for distribution in chromatographic systems, suggesting potential in drug permeability or affinity processes. The compound exhibits notable biological activities, including trypanocidal activity against the bloodstream form of Trypanosoma cruzi Y, with an IC50 of 12300.0 nM. It also shows cytotoxicity against mouse embryo cells (HMC), with an LC50 of 41300.0 nM, yielding a selectivity index of 3.6. In human cells, 2-Chloronaphthoquinone displays cytotoxicity against THLE cells with varying EC50 values (21100.0 nM at 4 hrs, 13800.0 nM at 24 hrs, and 37400.0 nM at 72 hrs) and induces ROS generation with an EC50 of 2500.0 nM. Cytotoxic activity is also observed against WI38 and HL60 cells, with IC50 values of 21580.0 nM for WI38 cells, and 6320.0 nM and 11480.0 nM for HL60 cells at 48 and 24 hours, respectively, showing a selectivity index of 3.32 favoring HL60 cells. Additionally, 2-Chloronaphthoquinone inhibits Schistosoma mansoni DHODH enzyme activity by 46.0% at a concentration of 250 uM using a DCIP reduction-based assay..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	2-Chloronaphthoquinone (2-Chloro-1,4-naphthoquinone) is a substituted naphthoquinone which is used as an insecticide and acaricide.
别名	2-氯-1,4-萘醌, 2-Chloro-1,4-naphthoquinone

化学信息

分子量	192.6
分子式	C₁₀H₅ClO₂
CAS No.	1010-60-2
Smiles	ClC1=CC(=O)C2=C(C=CC=C2)C1=O
密度	1.42 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 60 mg/mL (311.53 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.1921 mL	25.9605 mL	51.9211 mL	259.6054 mL
5 mM	1.0384 mL	5.1921 mL	10.3842 mL	51.9211 mL
10 mM	0.5192 mL	2.5961 mL	5.1921 mL	25.9605 mL
20 mM	0.2596 mL	1.2980 mL	2.5961 mL	12.9803 mL
50 mM	0.1038 mL	0.5192 mL	1.0384 mL	5.1921 mL
100 mM	0.0519 mL	0.2596 mL	0.5192 mL	2.5961 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。