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Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)

产品编号 TMPJ-00557Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)

Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35 KDa and the accession number is AAH40887.1.

Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)

Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)

产品编号 TMPJ-00557Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)
Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35 KDa and the accession number is AAH40887.1.
规格价格库存数量
10 μg
¥ 1,170
5日内发货
50 μg
¥ 3,470
5日内发货
500 μg
¥ 12,100
5日内发货
1 mg
¥ 17,400
5日内发货
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常见问题解答
化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别?盐形式和游离态有什么区别?
盐和非盐形式化合物的活性分子是一样的,在生物实验中起到的效果也一致,活性和使用方法都是一样的。只是由于呈盐不同,物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。
如何选择某个靶点的特异性或总的抑制剂?特异性和非特异性的区别是什么?
抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂,对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。 一般评价一个抑制剂的抑制效率主要看 IC50 值,IC50 值越低,说明抑制剂效率越高。建议您根据以上几个特征进行综合选择,也可联系技术帮您推荐相关抑制剂。
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产品信息

生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述
Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35 KDa and the accession number is AAH40887.1.
种属
Human
表达系统
HEK293 Cells
标签C-6xHis
蛋白编号AAH40887.1
别名
Tumor-Associated Differentially Expressed Gene 14 Protein,TADG14,Serine Protease TADG-14,Serine Protease 19,PRSS19,Ovasin,NRPN,NP,Neuropsin,KLK8,Kallikrein-8,hK8
氨基酸序列
Gln29-GLy260
蛋白构建
Gln29-GLy260
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量35 KDa (reducing condition)
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
存储
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

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