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顶部相关产品产品介绍化学信息储存和溶解信息计算器

N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone

货号 T36988Cas号 273734-65-9 一键复制产品信息
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N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone is a long-chain N-acyl-homoserine lactone (AHL) produced by some Gram-negative bacteria and is involved in quorum sensing. Quorum sensing enables bacteria to change gene expression based on cues from nearby bacteria and from eukaryotic hosts about nutrients, environmental conditions, or threats. Due to the benefit of quorum sensing for bacterial survival, quorum sensing molecules are potential targets for controlling bacterial infections. In mouse and human leukocyte immunoassays using LPS-stimulated macrophages, N-(3-hydroxy-7-cis tetradecenoyl)-L-homoserine lactone did not have an effect on cytokine or antibody production.

N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone

一键复制产品信息
Rating icon 还可以
货号 T36988Cas号 273734-65-9

N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone is a long-chain N-acyl-homoserine lactone (AHL) produced by some Gram-negative bacteria and is involved in quorum sensing. Quorum sensing enables bacteria to change gene expression based on cues from nearby bacteria and from eukaryotic hosts about nutrients, environmental conditions, or threats. Due to the benefit of quorum sensing for bacterial survival, quorum sensing molecules are potential targets for controlling bacterial infections. In mouse and human leukocyte immunoassays using LPS-stimulated macrophages, N-(3-hydroxy-7-cis tetradecenoyl)-L-homoserine lactone did not have an effect on cytokine or antibody production.

N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone
规格价格库存数量
1 mg
¥ 1,080
35日内发货
5 mg
¥ 4,880
35日内发货
10 mg
¥ 8,630
35日内发货
25 mg
¥ 18,800
35日内发货
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产品介绍

生物活性
产品描述
N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone is a long-chain N-acyl-homoserine lactone (AHL) produced by some Gram-negative bacteria and is involved in quorum sensing. Quorum sensing enables bacteria to change gene expression based on cues from nearby bacteria and from eukaryotic hosts about nutrients, environmental conditions, or threats. Due to the benefit of quorum sensing for bacterial survival, quorum sensing molecules are potential targets for controlling bacterial infections. In mouse and human leukocyte immunoassays using LPS-stimulated macrophages, N-(3-hydroxy-7-cis tetradecenoyl)-L-homoserine lactone did not have an effect on cytokine or antibody production.
化学信息
分子量325.44
分子式C18H31NO4
CAS No.273734-65-9
SmilesN(C(CC(CCC/C=C\CCCCCC)O)=O)[C@@H]1C(=O)OCC1
储存&溶解度
存储
溶解度信息
DMF: 20 mg/mL (61.46 mM), Sonication is recommended.
Ethanol: 2 mg/mL (6.15 mM), Sonication is recommended.
DMSO: 20 mg/mL (61.46 mM), Sonication is recommended.
DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL (1.54 mM), Sonication is recommended.
溶液配制表
1mg5mg10mg50mg
1 mM3.0728 mL15.3638 mL30.7276 mL153.6382 mL
Ethanol/DMF/DMSO
1mg5mg10mg50mg
5 mM0.6146 mL3.0728 mL6.1455 mL30.7276 mL
DMF/DMSO
1mg5mg10mg50mg
10 mM0.3073 mL1.5364 mL3.0728 mL15.3638 mL
20 mM0.1536 mL0.7682 mL1.5364 mL7.6819 mL
50 mM0.0615 mL0.3073 mL0.6146 mL3.0728 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

N(3hydroxy7cis tetradecenoyl)LHomoserine lactoneN (3 hydroxy 7 cis tetradecenoyl) L Homoserine lactone
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