Propantheline (10 μM-1 mM) decreases urinary bladder smooth muscle reactivity to Acetylcholine [1].

Propantheline (oral administration, 10-300 mg/kg) decreased the fecal pellet count and the incidences diarrhea in restraint stress-induced bowel dysfunction rats [3]. Animal Model: Restraint stress-induced bowel dysfunction models in rats [3] Dosage: 10-300 mg/kg Administration: Oral administration Result: Decreased the fecal pellet count with ED 50 values of 41 mg/kg. Dose-dependently decreased the incidences of diarrhea with ED50 values of 64 mg/kg.