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Anti-PCSK9 Antibody (3B17)

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产品编号 TMAY-03671
别名 proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3

Anti-PCSK9 Antibody (3B17) 是一种 Mouse 抗体,靶向 PCSK9。Anti-PCSK9 Antibody (3B17) 可用于 ELISA。

Anti-PCSK9 Antibody (3B17)

Anti-PCSK9 Antibody (3B17)

Rating icon 还可以
产品编号 TMAY-03671 别名 proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3

Anti-PCSK9 Antibody (3B17) 是一种 Mouse 抗体,靶向 PCSK9。Anti-PCSK9 Antibody (3B17) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-PCSK9 Antibody (3B17) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (3B17) can be used in ELISA.
别名proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3
Ig Type
Monoclonal Mouse IgG1
克隆号
3B17
交叉反应
Rat
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat PCSK9 (rR PCSK9; TMPY-01565; NP_954862.2; Met 1-Gln 691). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Rat PCSK9 protein (TMPY-01565)
抗原种属
Rat
研究领域
Serine Proteases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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