购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
TargetMol | Compound Library

高溶解性多官能团片段化合物库现货

High Solubility Polyfunctional Group Fragment Library

Rating icon 很棒
产品编号 L7810

高溶解性多官能团片段库的设计原则是,为化学合成提供性价比高,反应快速的稳定片段化合物。稳定的片段包含至少两个可参与化学反应的官能团。这些反应包括酰胺偶联、铃木型芳基-芳基偶联和还原胺化等。高溶解性多官能团片段库包含1158 种片段分子

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。
资源下载
化合物库相关信息
Excel
SDF
联系我们获取更多批次信息

产品编号 L7810

高溶解性多官能团片段化合物库

规格

  • 1 mg
  • 5 mg
  • 10 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

Product Description Product Description

Traditional drug research and development are mainly based on natural active products or screening new drugs from existing compound data, but this method is highly random, blind, and inefficient. Medicinal chemists subsequently developed high-throughput screening (HTS) methods for drug discovery. Many pharmaceutical companies have also established compound libraries containing millions of small molecules and discovered many drug candidates. However, in drug screening with complex targets, HTS has been repeatedly frustrated. It is difficult to screen high-potential compounds, or the screened compounds have high false positives and poor drug-like properties. In this context, Fragment-based drug design (FBDD) came into being.
The theoretical basis of FBDD is to select favorable fragment combinations or extensions to obtain new drug molecules, with a higher probability of obtaining highly active drug candidates. Compared with the screening of millions of macromolecules, thousands of fragment molecules can be combined to form millions of drug structures, which are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. The high solubility multifunctional fragment library is designed by analyzing the spatial stability of all commercially available fragments and selecting a chemically diverse subset. In order to enhance the diversity of the compound library, we carefully selected some additional saturated heterocyclic compounds to supplement the compound library.

Core skeleton structure:

Core skeleton structure:

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

使用TargetMol产品
发表顶级期刊文献

引用更多关于TargetMol产品的科学文献吧!

查看更多

Library Customization | TargetMol 化合物库定制

Compound Library | TargetMol
您可以通过点击按钮
定制您专属的化合物!
联系专属定制

Library Customization | TargetMol 化合物库组成

ADC Linker
Histamine Receptor
COX
Apoptosis
HIV Protease
Carbonic Anhydrase
Antifungal
DNA Alkylator/Crosslinker
MRP
PPAR
PDE
Drug Metabolite
MMP
Antibacterial
DNA/RNA Synthesis
Autophagy
Free radical scavengers
Sodium Channel

Supporting Files | TargetMol 化合物库信息

Empty99-92-399-88-799347-30-599169-50-399-05-899-03-698634-00-598557-04-198-10-297108-50-4Empty
Compound Fr13850Compound Fr13988Compound Fr12930Compound Fr12361Compound PDK0420Compound Fr14102Compound Fr13397Compound Fr13595BenzenesulfonamideCompound Fr14488
Empty97051-69-9960079-47-4958443-30-695727-77-895725-34-195539-61-095373-40-3952182-05-795-17-0950603-22-2Empty
Compound Fr13290Compound FL0236Compound Fr13074Compound Fr12494Compound Fr13539Compound Fr12759Compound Fr13540Compound FL0103Compound Fr13657Compound Fr13681
Empty950603-17-5949922-52-5946713-86-694-64-4945217-60-794-09-793983-13-2939801-34-0937796-17-3937796-07-1Empty
Compound Fr12315Compound FL0114Compound Fr12496N-(2-CHLOROBENZYL)-N-METHYLAMINECompound FL0199BenzocaineCompound Fr12975Compound FL0243Compound Fr13322Compound Fr13258
Empty937795-86-3936083-53-3936083-51-1936083-46-4936083-43-1936083-40-8936083-37-3936083-19-1934570-57-7934570-47-5Empty
Compound Fr12753Compound Fr12994Compound Fr13503Compound Fr12482Compound Fr12861Compound Fr16708Compound Fr12696Compound Fr16727Compound Fr13149Compound Fr13031
Empty93296-41-493189-16-393138-55-7930111-07-2930111-04-9927679-54-792733-82-992288-27-2921939-11-992146-82-2Empty
Compound Fr13247Compound Fr12910Compound Fr12678Compound Fr13393Compound Fr14521Compound FL0066Compound Fr13207Compound Fr14263Compound Fr12911Compound Fr12784
Empty92057-12-092-00-2916766-86-4916766-82-0915707-57-2915707-49-2913830-33-8912569-78-991076-93-6910037-08-0Empty
Compound Fr12264Compound Fr13267Compound Fr14566Compound Fr12189Compound Fr13488Compound Fr13318Compound Fr13073Compound Fr13682Compound Fr13823Compound Fr12202
Empty910037-07-9910037-06-8910037-04-6910037-03-590719-32-7906352-71-4906352-66-790396-06-890322-18-290-31-3Empty
Compound Fr13487Compound Fr13367Compound Fr13366Compound Fr13365(S)-4-Benzyl-2-oxazolidinoneCompound Fr13352Compound Fr13377Compound Fr13449Compound Fr14141Compound Fr13156
Empty90296-27-889999-90-689-97-4898289-40-2898289-35-589-77-0893742-71-789353-42-489-25-889250-34-0Empty
Compound Fr12176Compound Fr14432Compound Fr14345Compound Fr13353Compound Fr12780Compound Fr12149Compound Fr13411Compound Fr14541EdaravoneCompound Fr12670