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Anti-HGF Antibody (2T167)

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Anti-HGF Antibody (2T167)
产品编号 TMAY-00858
别名 肝细胞生长因子, scatter factor), hepatocyte growth factor (hepapoietin A

Anti-HGF Antibody (2T167) 是一种 Mouse 抗体,靶向 HGF。Anti-HGF Antibody (2T167) 可用于 ELISA。

Anti-HGF Antibody (2T167)
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Anti-HGF Antibody (2T167)

Rating icon 还可以
Anti-HGF Antibody (2T167)
产品编号 TMAY-00858 别名 肝细胞生长因子, scatter factor), hepatocyte growth factor (hepapoietin A

Anti-HGF Antibody (2T167) 是一种 Mouse 抗体,靶向 HGF。Anti-HGF Antibody (2T167) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-HGF Antibody (2T167) is a Mouse antibody targeting HGF. Anti-HGF Antibody (2T167) can be used in ELISA.
别名肝细胞生长因子, scatter factor), hepatocyte growth factor (hepapoietin A
Ig Type
Mouse IgG1
克隆号
2T167
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HGF / Hepatocyte Growth Factor (rh HGF / Hepatocyte Growth Factor; NP_000592.3Met 1-Ser 728). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by mesenchymal cells as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor, and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility and matrix invasion give it a central role in angiogenesis, tumorogenesis, and tissue regeneration. HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF has no detectable protease activity. Defects in hepatocyte growth factor are the cause of deafness autosomal recessive type 39. A form of profound prelingual sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human HGF / Hepatocyte Growth Factor protein
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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