Name: Picroside IV
Brand: TargetMol
SKU: TN2072
Price: 578 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 578

现货

5 mg

¥ 1,390

现货

10 mg

¥ 2,090

现货

25 mg

¥ 3,530

现货

50 mg

¥ 4,970

现货

100 mg

¥ 7,250

现货

产品介绍

生物活性

产品描述	Picroside IV is an iridoid glycoside originating from the underground parts of Picrorhiza scrophulariiflora and serves as a derivative of Catalpol while demonstrating broad pharmacological functions including neuroprotective, hypoglycemic, anti-inflammatory, anticancer, antispasmodic, antioxidant, and anti-HBV effects. Picroside IV therefore represents a therapeutically valuable bioactive molecule with high relevance in disease prevention and treatment research.
体外活性	药代动力学研究结果显示，TGPR中的6种成分（picroside I, picroside II, vanillic acid, androsin, cinnamic acid 和 Picroside IV）可被快速吸收且缓慢消除，其生物利用度均低于12.37%，这表明灌胃给药后药物吸收效果较差。在组织分布方面，TGPR中的6种成分均能在肝脏中被检测到，且仅androsin可穿透血脑屏障。同时，排泄研究表明：vanillic acid主要以原型药物形式排出体外；其余 5 种成分则可能在体内发生广泛代谢并以代谢产物形式存在，其未转化的原型药物主要通过粪便途径排出 [1]。
别名	胡黄连苷 IV

化学信息

分子量	508.47
分子式	C₂₄H₂₈O₁₂
CAS No.	211567-04-3
Smiles	C(O)[C@@]12[C@@](O1)([C@@H](O)[C@]3([C@@]2([C@H](O[C@@H]4O[C@H](COC(/C=C/C5=CC=C(O)C=C5)=O)[C@@H](O)[C@H](O)[C@H]4O)OC=C3)[H])[H])[H]
密度	1.62 g/cm3 (Predicted)
颜色	White
物理性状	Solid

储存&溶解度

存储

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 80 mg/mL (157.33 mM), Sonication is recommeded.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9667 mL	9.8334 mL	19.6668 mL	98.3342 mL
5 mM	0.3933 mL	1.9667 mL	3.9334 mL	19.6668 mL
10 mM	0.1967 mL	0.9833 mL	1.9667 mL	9.8334 mL
20 mM	0.0983 mL	0.4917 mL	0.9833 mL	4.9167 mL
50 mM	0.0393 mL	0.1967 mL	0.3933 mL	1.9667 mL
100 mM	0.0197 mL	0.0983 mL	0.1967 mL	0.9833 mL

体内实验配液计算器