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Sting Protein, Human, Recombinant (Sumo & His)

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纯度: 98%

货号 TMPJ-01206

别名 TMEM173, sting, Stimulator of interferon genes protein, Mediator of IRF3 activation

Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.

Sting Protein, Human, Recombinant (Sumo & His)
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Sting Protein, Human, Recombinant (Sumo & His)

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Rating icon 很棒

纯度: 98%

货号 TMPJ-01206 别名 TMEM173, sting, Stimulator of interferon genes protein, Mediator of IRF3 activation

Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.

规格价格库存数量
5 μg
¥ 492
现货
10 μg
¥ 820
现货
20 μg
¥ 1,290
现货
50 μg
¥ 2,480
现货
100 μg
¥ 3,980
现货
200 μg
¥ 6,420
5日内发货
500 μg
¥ 12,100
5日内发货
1 mg
¥ 17,300
5日内发货
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选择批次:
纯度: Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
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资源下载:
COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.
种属
Human
表达系统
E. coli
标签N-Sumo-6xHis
蛋白编号Q86WV6
氨基酸序列Val155-Val341
蛋白构建Val155-Val341
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Sting Protein, Human, Recombinant (Sumo & His)
缓冲液Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 100 mM NaCl, 10% Glycerol, pH8.0.
别名TMEM173, sting, Stimulator of interferon genes protein, Mediator of IRF3 activation
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量35 KDa (reducing condition)
颜色Transparent
物理性状Liquid
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

TMEM-173TMEM 173
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