Name: BLK Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00307
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 492

6-8日内发货

10 μg

¥ 820

6-8日内发货

20 μg

¥ 1,290

2-4周

50 μg

¥ 2,480

2-4周

100 μg

¥ 3,980

2-4周

200 μg

¥ 6,420

2-4周

500 μg

¥ 12,100

2-4周

1 mg

¥ 17,300

2-4周

生物活性

产品描述	Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).
种属	Human
表达系统	E. coli
标签	C-6xHis
蛋白编号	P51451
氨基酸序列	Gly2-Pro505
蛋白构建	Gly2-Pro505
蛋白纯度	Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
缓冲液	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 500 mM NaCl, 1 mM DTT, pH 7.4.
别名	Tyrosine-Protein Kinase Blk, p55-Blk, BLK, B Lymphocyte Kinase
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.

化学信息

分子量	50-65 KDa (reducing condition)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

BLK Protein, Human, Recombinant (His)

BLK Protein, Human, Recombinant (His)

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