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Claudin-18.2 Protein, Human, Recombinant (Insect, His)

产品编号 TMPS-00018

Claudin-18.2 Protein, Human, Recombinant (Insect, His) is expressed in Baculovirus Insect Cells. The accession number is P56856-2.

产品编号 TMPS-00018

Claudin-18.2 Protein, Human, Recombinant (Insect, His) is expressed in Baculovirus Insect Cells. The accession number is P56856-2.

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生物活性	Immobilized CLDN18.2, His, Human (Cat. No.: Z03504) at 1.0 μg/mL (100μl/well). Dose response curve for anti-Claudin 18.2 Antibody with the EC 50 of 13.75ng/mL determined by ELISA.
产品描述	Claudin-18.2 Protein, Human, Recombinant (Insect, His) is expressed in Baculovirus Insect Cells. The accession number is P56856-2.
种属	Human
表达系统	Baculovirus Insect Cells
标签	His
蛋白编号	P56856-2
别名	SFTPJ,SFTA5,CLDN18,Claudin-18,claudin 18
蛋白构建	Met1-Lys207
蛋白纯度	> 80% as determined by SDS-PAGE
分子量	27.7 kDa (Predicted)
缓冲液	Supplied as a solution in 50 mM Hepes, 500 mM NaCl, 10% glycerol, 0.2% DDM, 0.04% CHS, pH 7.5.
存储	Upon receiving, this product remains stable for up to 6 months at -80°C. Please avoid repeated freeze-thaw cycles.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. The Expression of Isoform A2 (CLDN18.2) is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level). CLDN18.2 is founded to be abundant in gastric tumors, Experimental antibody IMAB362 targets Claudin 18.2 to help treat gastric cancers.