|
TMPH-00007
|
HMGCR Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs. |
|
TMPH-00009
|
OGT Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross-talk between glycosylation and phosphorylation or by affecting proteolytic processing. Probably by glyco... |
|
TMPH-00010
|
MMP-14 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to... |
|
TMPH-02283
|
USP18 Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
USP18 Protein, Human, Recombinant (His) is expressed in E. coli with N-terminal 6xHis tag. The predicted molecular weight is 47.1 kDa. Accession number: Q9UMW8 |
|
TMPU-00003
|
STAT2 Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of... |
|
TMPY-00082
|
PLP-C beta Protein, Rat, Recombinant (His)
Prlpc2,PLP-C β Protein, Rat, Recombinant (His),prol...
|
Rat
|
HEK293
|
|
PLP-C beta Protein, Rat, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 25.8 kDa. Accession number: A0A0M6L0Y1 |
|
TMPK-00943
|
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
PDGF R α/PDGFRA Protein, Cynomolgus, Recombinant (H...
|
Cynomolgus
|
HEK293
|
|
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. |
|
TMPH-00008
|
SOX-2 Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Binds to the proximal enhancer region of NANOG. Critical for early embryogenesis and for embryonic stem cell pluripotency. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses n... |
|
TMPK-00419
|
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
RHEPDGFRA,PDGFR-2,CD140A,PDGFR2,MGC74795,PDGF R α/PDGFRA Pro...
|
Human
|
HEK293
|
|
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. |
|
TMPK-00420
|
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
RHEPDGFRA,PDGFRA,PDGF R α/PDGFRA Protein, Human, Recombi...
|
Human
|
HEK293
|
|
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. |
|
TMPH-03764
|
YAP1 Protein, Human, Recombinant (His)
YAP1-2gamma,YAP2L,YAP65
|
Human
|
Yeast
|
|
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1,... |
|
TMPH-00011
|
Ataxin-8 Protein, Human, Recombinant (His)
ATXN8,Protein 1C2,Ataxin-8
|
Human
|
E. coli
|
|
Ataxin-8 Protein, Human, Recombinant (His) is expressed in E. coli. The predicted molecular weight is . Accession number: Q156A1 |
|
TMPY-04408
|
CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)
calcium/calmodulin-dependent protein kinase II beta,CAM2,CAM...
|
Human
|
Baculovirus-Insect Cells
|
|
Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in prostate cancer cells ability to escape apoptosis under androgen ablation and facilitate the progression of prostate cancer cells to an androgen independent state. As a multifunctional protein kinase, the loss of activity may play a critical role in initiating the changes leading to... |
|
TMPJ-01473
|
BMP-7 Protein, Human, Recombinant
Eptotermin alfa,OP-1,OP1,Osteogenic protein 1,Bone morphogen...
|
Human
|
Human Cells
|
|
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a... |
|
TMPJ-01472
|
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)
|
Mouse
|
Human Cells
|
|
Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune respo... |
|
TMPH-00001
|
CD133/PROM1 Protein-VLP, Human, Recombinant (His)
Proml1,Prom1,CD133,Prominin-like protein 1,Antigen AC133 hom...
|
Human
|
HEK293
|
|
May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. |
|
TMPU-00004
|
STAT5A Protein, Human, Recombinant (His)
MGF,Signal transducer and activator of transcription 5A
|
Human
|
E. coli
|
|
Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate cancer. Until recently, the unique characteristics and function of STAT5a in these cancers have not been delineated from STAT5b, and more research into their differential behavior is warranted. Because of its integral role in immune cell development, STAT5a may contribute to tumor de... |
|
TMPK-01398
|
CD40 Ligand Trimer Protein, Human, Recombinant (hFc)
CD40 Ligand,CD40LIGM,IGM,gp39,TNFSF5,TRAP,HIGM1,CD154,TNFSF5...
|
Human
|
HEK293
|
|
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. |
|
TMPU-00002
|
SOS1-Cat Protein, Human, Recombinant (His)
SOS-1,Son of sevenless homolog 1
|
Human
|
E. coli
|
|
Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1) [MIM:135300]; also known as GINGF1. Gingival fibromatosis is a rare overgrowth condition. Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4) [MIM:610733]. NS4 is an autosomal dominant disorder characterized by dysmorphic facial features, short stature, hypertelorism, cardiac anomalies, deafness, motor delay, and a bleeding diathesis. It is a genetically heterogeneous and relatively common syndrome, with an estimated incid... |
|
TMPY-04204
|
Recombinant Protein L
|
|
E. coli
|
|
Recombinant Protein L is expressed in HEK293 E. coli. |
|
TMPY-00125
|
Recombinant Protein A
|
|
E. coli
|
|
Staphylococcal Protein A, or SPA, is a type I membrane protein covalently linked to the cell wall of most strains of the Gram-positive bacterium Staphylococcus aureus. It has high affinity to IgG from various species, for instance human, rabbit and guinea pig but only weak interaction with bovine and mouse. Protein A interacts with antibodies through two distinct binding events: the “classical” binding site on the Fc portion of human IgG1, IgG2, and IgG4, and the “alternate” binding site found o... |
|
TMPJ-00824
|
Ig lambda constant 2 Protein, Human, Recombinant (His)
Ig λ constant 2 Protein, Human, Recombinant (His),M...
|
Human
|
Human Cells
|
|
Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. IGLC2 is 105 amino acids (aa) in length. I... |
|
TMPY-00105
|
Recombinant Protein G
|
|
E. coli
|
|
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains.
It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig... |
|
TMPY-02511
|
PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)
LRP,PTP α/PTPRA Protein, Human, Recombinant (aa 174...
|
Human
|
Baculovirus-Insect Cells
|
|
PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTPRA could promote the cell cycle progression through stimulating the c-Src signaling pathways. The PTPRA gene, which encodes the protein RPTP-alpha, is critical to neurodevelopment. Previous linkage studies, genome-wide association studies, controlled expression analyses and anima... |
|
TMPY-01132
|
COL6A3 Protein, Human, Recombinant
collagen, type VI, α3,collagen, type VI, alpha 3
|
Human
|
HEK293
|
|
COL6A3 Protein, Human, Recombinant is expressed in HEK293 cells. |
|
TMPY-01010
|
NGF Protein, Human, Recombinant
Beta-NGF,神经生长因子,β-NGF,NGFB,nerve growth factor (β polypeptid...
|
Human
|
CHO
|
|
NGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 13.2 kDa and the accession number is P01138. |
|
TMPY-03274
|
CXCL11 Protein, Human, Recombinant
SCYB9B,I-TAC,chemokine (C-X-C motif) ligand 11,H174,SCYB11,I...
|
Human
|
E. coli
|
|
I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC ... |
|
TMPY-04104
|
LIF Protein, Human, Recombinant
CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HILDA
|
Human
|
HEK293
|
|
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone metabolism, cachexia, neural development, embryogenesis, and inflammation. LIF has potent proinflammatory properties, being the inducer of the acute phase protein synthesis and affecting cell recruitment into the area of damage or inflammation. LIF is also one of the cytokines that ... |
|
TMPY-04278
|
LIF Protein, Mouse, Recombinant
白血病抑制因子,leukemia inhibitory factor
|
Mouse
|
HEK293
|
|
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone metabolism, cachexia, neural development, embryogenesis, and inflammation. LIF has potent proinflammatory properties, being the inducer of the acute phase protein synthesis and affecting cell recruitment into the area of damage or inflammation. LIF is also one of the cytokines that ... |
|
TMPY-04330
|
Mer Protein, Human, Recombinant
MER proto-oncogene, tyrosine kinase,RP38,MER,c-mer,Tyro12,c-...
|
Human
|
HEK293
|
|
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MERTK is localized in the membrane and is no expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines. This protein is highly expressed in the testis, ovary, prostate, lung, and kidney, with ... |
|
TMPY-02881
|
RAGE Protein, Human, Recombinant
RAGE,advanced glycosylation end product-specific receptor
|
Human
|
HEK293
|
|
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, an... |
|
TMPY-04803
|
DLL4 Protein, Human, Recombinant
δ-like 4 (Drosophila),delta-like 4 (Drosophila),Delta-like 4...
|
Human
|
HEK293
|
|
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent studies yield substantial insights into the role of DLL4 in angiogenesis. DLL4 is induced by vascular endothelial growth factor (VEGF) and acts downstream of VEGF as a 'brake' on VEGF-induced vessel growth, forming an autoregulatory negative feedback loop inactivating VEGF. DLL4 is d... |
|
TMPY-00132
|
Mesothelin Protein, Human, Recombinant
MPF,SMRP,Mesothelin
|
Human
|
HEK293
|
|
The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamo... |
|
TMPY-03441
|
SAE1 Protein, Human, Recombinant
SUA1,SUMO1 activating enzyme subunit 1,HSPC140,UBLE1A,AOS1
|
Human
|
Baculovirus-Insect Cells
|
|
SAE1 belongs to the ubiquitin-activating E1 family. It is a heterodimer that acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It functions as a UBLI E1 ligase mediating the ATP-dependent activation of UBL1. SAE1 binds with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. SAE1 also regulates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activati... |
|
TMPJ-00166
|
SCF Protein, Mouse, Recombinant
SCF,Hematopoietic growth factor KL,MGF,Steel factor,Mast cel...
|
Mouse
|
E. coli
|
|
Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the ... |
|
TMPY-04750
|
CSNK2A2 Protein, Human, Recombinant
CK2A2,CSNK2A1,casein kinase 2, alpha prime polypeptide,casei...
|
Human
|
Baculovirus-Insect Cells
|
|
Casein kinase II subunit alpha', also known as CSNK2A2 and CK2A2, is a member of the protein kinase superfamily, Ser/Thr protein kinase family and CK2 subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. CSNK2A2 is a tetramer composed of an alpha chain, an alpha' and two beta chains. It is also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, S... |
|
TMPY-03290
|
HGF Protein, Mouse, Recombinant
hepatocyte growth factor (hepapoietin A,NK1,scatter factor),...
|
Mouse
|
HEK293
|
|
Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by mesenchymal cells as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The hepatocyte growth factor regulates cell growt... |
|
TMPY-01717
|
VEGF164 Protein, Mouse, Recombinant
vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子
|
Mouse
|
Baculovirus-Insect Cells
|
|
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... |
|
TMPY-02327
|
HGF Protein, Human, Recombinant
SF,hepatocyte growth factor (hepapoietin A,HGFB,F-TCF,F-TCFB...
|
Human
|
CHO
|
|
Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by mesenchymal cells as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The hepatocyte growth factor regulates cell growt... |
|
TMPY-03432
|
KEAP1 Protein, Human, Recombinant
kelch like ECH associated protein 1,INRF2,KLHL19,KEAP-1
|
Human
|
Baculovirus-Insect Cells
|
|
Kelch-like ECH-associated protein 1, also known as a cytosolic inhibitor of Nrf2, Kelch-like protein 19, KEAP1, and INRF2, is a cytoplasm and nucleus protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain, and six Kelch repeats. KEAP1 / INRF2 is broadly expressed, with the highest levels in skeletal muscle. KEAP1 / INRF2 is a key regulator of the NRF2 transcription factor, which transactivates the antioxidant response element (ARE) and upregulates numerous proteins in... |
|
TMPY-03050
|
CXCL5 Protein, Human, Recombinant
ENA-78,SCYB5,chemokine (C-X-C motif) ligand 5
|
Human
|
E. coli
|
|
CXCL5 is a small cytokine belonging to the CXC chemokine family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. CXCL5 is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. It also can be detected in eosinophils, and can be inhibited with the type II interferon. CXCL5 plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utili... |
|
TMPY-01560
|
EGF Protein, Human, Recombinant
URG,epidermal growth factor,表皮生长因子,HOMG4
|
Human
|
E. coli
|
|
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds. As a low-molecular-weight polypeptide, EGF was first purified from the mouse submandibular gland, but since then it was found in many human tissues including submandibular gland, ... |
|
TMPY-03698
|
VEGF121b Protein, Human, Recombinant
MVCD1,VEGF,VPF,vascular endothelial growth factor A
|
Human
|
HEK293
|
|
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... |
|
TMPY-03782
|
Albumin Protein, Human, Recombinant
PRO0883,albumin,FDAH,PRO0903,PRO1341,ANALBA
|
Human
|
Yeast
|
|
Albumin Protein, Human, Recombinant is expressed in HEK293 cells. |
|
TMPJ-00042
|
TSLP Protein, Human, Recombinant
TSLP,Thymic stromal lymphopoietin
|
Human
|
E. coli
|
|
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral... |
|
TMPY-03484
|
TCPTP Protein, Human, Recombinant
TCPTP,protein tyrosine phosphatase, non-receptor type 2,PTPT...
|
Human
|
Baculovirus-Insect Cells
|
|
Tyrosine-protein phosphatase non-receptor type 2, also known as T-cell protein-tyrosine phosphatase, PTPN2 and PTPT, is a cytoplasm protein that belongs to the protein-tyrosine phosphatase family and Non-receptor class 1 subfamily. Members of the protein tyrosine phosphatase ( PTP ) family share a highly conserved catalytic motif, which is essential for the catalytic activity. TC-PTP / PTPN2 is a cytosolic tyrosine phosphatase that functions as a negative regulator of a variety of tyrosine kinas... |
|
TMPY-02432
|
VEGF164 Protein, Rat, Recombinant
血管内皮生长因子,vascular endothelial growth factor A
|
Rat
|
Baculovirus-Insect Cells
|
|
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... |
|
TMPY-02521
|
HIST3H2A Protein, Human, Recombinant
histone cluster 3, H2a,MGC3165
|
Human
|
E. coli
|
|
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enzymatic machinery that set them are crucial regulators that can control cellular proliferation, differentiation,... |
|
TMPY-02970
|
CXCL10 Protein, Human, Recombinant
IFI10,IP-10,chemokine (C-X-C motif) ligand 10,gIP-10,crg-2,C...
|
Human
|
E. coli
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(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic ... |
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TMPY-02234
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CXCL9 Protein, Human, Recombinant
MIG,CMK,Humig,chemokine (C-X-C motif) ligand 9,SCYB9,crg-10
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Human
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E. coli
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Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defined; however, it is thought to be involved in T cell trafficking. CXCL9/MIG functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. CXCL9/MIG, together with CXCL10 and CXCL11, may activate CXCR3 by bi... |
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