生物活性

产品描述	CEACAM7 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q14002-1.
生物活性	Immobilized Human CEACAM-3, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human CEACAM-7, hFc Tag with the EC50 of 26.5 ng/ml determined by ELISA.
研究背景	Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell–cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAM7 (CGM2), a member of the CEA family of proteins with expression restricted to the colon and pancreas, as a potential CAR T-cell target for PDAC.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc (IgG1)
蛋白编号	Q14002-1
蛋白构建	Thr36-Ser242
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	50.11 kDa (Predicted); 68-78 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

CEACAM7 Protein, Human, Recombinant (hFc)

CEACAM7 Protein, Human, Recombinant (hFc)

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