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Fas Ligand Protein, Human, Recombinant (HEK293, His)

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产品编号 TMPY-03956U

Fas Ligand Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is AAH17502.1.

Fas Ligand Protein, Human, Recombinant (HEK293, His)

一键复制产品信息

产品编号 TMPY-03956U

Fas Ligand Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is AAH17502.1.

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生物活性	Immobilized Human Fas Ligand, His Tag at 2 μg/ml (100 μl/Well) on the plate. Dose response curve for Human Fas, hFc Tag with the EC50 of 0.19 μg/ml determined by ELISA (QC Test). Human Fas, His Tag immobilized on CM5 Chip can bind Human Fas Ligand, His Tag with an affinity constant of 19.45 nM as determined in SPR assay (Biacore T200).
产品描述	Fas Ligand Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is AAH17502.1.
种属	Human
表达系统	HEK293 Cells
标签	N-His
蛋白编号	AAH17502.1
蛋白构建	Pro134-Leu281
蛋白纯度	> 95% as determined by Tris-Bis PAGE
分子量	18 kDa (Predicted); 20-35 kDa (Due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Fas ligand (FasL, CD95L) is a 40-kDa type II transmembrane protein that binds to Fas (CD95) receptors and promotes programmed cell death. Fas receptors are expressed at higher levels in many tumors than in normal cells.Somewhat paradoxically, elimination of Fas or FasL from tumors also leads to death induced by CD95 receptor/ligand elimination (DICE).