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Anti-Phospho-PDHA1 (Ser293) Antibody (2F819) 是一种 Rabbit 抗体,靶向 Phospho-PDHA1 (Ser293)。Anti-Phospho-PDHA1 (Ser293) Antibody (2F819) 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-Phospho-PDHA1 (Ser293) Antibody (2F819) 是一种 Rabbit 抗体,靶向 Phospho-PDHA1 (Ser293)。Anti-Phospho-PDHA1 (Ser293) Antibody (2F819) 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-Phospho-PDHA1 (Ser293) Antibody (2F819) is a Rabbit antibody targeting Phospho-PDHA1 (Ser293). Anti-Phospho-PDHA1 (Ser293) Antibody (2F819) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 2F819 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Mitochondrion matrix. |
| 组织特异性 | Testis. Expressed in postmeiotic spermatogenic cells. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase(E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| 免疫原 | A synthesized peptide: human PDHA1 around the phosphorylation site of S293 |
| 抗原种属 | Human |
| 基因名称 | PDHA1 |
| 基因ID | |
| 蛋白名称 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial |
| Uniprot ID | |
| 功能 | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. |
| 分子量 | Theoretical: 40 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |