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顶部生物活性储存和溶解信息计算器

Anti-Phospho-STAT5A (Tyr694) Antibody (4G666)

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产品编号 TMAB-11325

Anti-Phospho-STAT5A (Tyr694) Antibody (4G666) 是一种 Rabbit 抗体，靶向 Phospho-STAT5A (Tyr694)。Anti-Phospho-STAT5A (Tyr694) Antibody (4G666) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-STAT5A (Tyr694) Antibody (4G666)

Anti-Phospho-STAT5A (Tyr694) Antibody (4G666)

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-11325

Anti-Phospho-STAT5A (Tyr694) Antibody (4G666) 是一种 Rabbit 抗体，靶向 Phospho-STAT5A (Tyr694)。Anti-Phospho-STAT5A (Tyr694) Antibody (4G666) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-STAT5A (Tyr694) Antibody (4G666) is a Rabbit antibody targeting Phospho-STAT5A (Tyr694). Anti-Phospho-STAT5A (Tyr694) Antibody (4G666) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
4G666
交叉反应
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Mostly cytoplasmic during pregnancy, whereas it becomes predominantly nuclear during early lactation. It is translocated into the nucleus in response to phosphorylation.
组织特异性Expressed in heart, lung, and weakly in muscle.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
A synthesized peptide: human p-STAT5A (Y694)
抗原种属
Human
基因名称
STAT5A
基因ID
6776
蛋白名称
Signal transducer and activator of transcription 5A
Uniprot ID
P42229
功能
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
化学信息
分子量Theoretical: 91 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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