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Anti-Transglutaminase 2 Antibody (7U519)

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货号 TMAB-13735

Anti-Transglutaminase 2 Antibody (7U519) 是一种 Rabbit 抗体，靶向 Transglutaminase 2。Anti-Transglutaminase 2 Antibody (7U519) 可用于 WB,IHC-P,IF,IHC-Fr。

Anti-Transglutaminase 2 Antibody (7U519)

Anti-Transglutaminase 2 Antibody (7U519)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13735

Anti-Transglutaminase 2 Antibody (7U519) 是一种 Rabbit 抗体，靶向 Transglutaminase 2。Anti-Transglutaminase 2 Antibody (7U519) 可用于 WB,IHC-P,IF,IHC-Fr。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Transglutaminase 2 Antibody (7U519) is a Rabbit antibody targeting Transglutaminase 2. Anti-Transglutaminase 2 Antibody (7U519) can be used in WB,IHC-P,IF,IHC-Fr.
Ig Type
IgG
克隆号
7U519
反应种属
Human,Mouse,Rat
应用WBIHC-PIFIHC-Fr
推荐剂量
WB: 1: 500- 2000; IHC-P: 1: 100- 500; IF: 1: 100- 500; IHC-Fr: 1: 100- 500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式Affinity Purification
性状Liquid
缓冲液PBS with 100 μg/ml BSA, 0.15% ProClin300 and 50% glycerol.
研究背景Calcium-dependent acyltransferase that catalyzes the formation of covalent bonds between peptide-bound glutamine and various primary amines, such as gamma-amino group of peptide-bound lysine, or mono- and polyamines, thereby producing cross-linked or aminated proteins, respectively. Involved in many biological processes, such as bone development, angiogenesis, wound healing, cellular differentiation, chromatin modification and apoptosis. Acts as a protein-glutamine gamma-glutamyltransferase by mediating the cross-linking of proteins, such as ACO2, HSPB6, FN1, HMGB1, RAP1GDS1, SLC25A4/ANT1, SPP1 and WDR54. Under physiological conditions, the protein cross-linking activity is inhibited by GTP; inhibition is relieved by Ca(2+) in response to various stresses. When secreted, catalyzes cross-linking of proteins of the extracellular matrix, such as FN1 and SPP1 resulting in the formation of scaffolds. Plays a key role during apoptosis, both by (1) promoting the cross-linking of cytoskeletal proteins resulting in condensation of the cytoplasm, and by (2) mediating cross-linking proteins of the extracellular matrix, resulting in the irreversible formation of scaffolds that stabilize the integrity of the dying cells before their clearance by phagocytosis, thereby preventing the leakage of harmful intracellular components.
抗原信息
免疫原
A synthesized peptide: human TGM2
抗原种属
Human
基因名称
TGM2
基因ID
7052
蛋白名称
Protein-glutamine gamma-glutamyltransferase 2
Uniprot ID
P21980
功能
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
化学信息
分子量Theoretical: 78 kDa. Actual: 78 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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