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Anti-TRIM29 Antibody (4W329) 是一种 Rabbit 抗体,靶向 TRIM29。Anti-TRIM29 Antibody (4W329) 可用于 WB。
Anti-TRIM29 Antibody (4W329) 是一种 Rabbit 抗体,靶向 TRIM29。Anti-TRIM29 Antibody (4W329) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,380 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-TRIM29 Antibody (4W329) is a Rabbit antibody targeting TRIM29. Anti-TRIM29 Antibody (4W329) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 4W329 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Colocalizes with intermediate filaments. |
| 组织特异性 | Expressed in placenta, prostate and thymus. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation. |
| 免疫原 | A synthesized peptide: human TRIM29 |
| 抗原种属 | Human |
| 基因名称 | TRIM29 |
| 基因ID | |
| 蛋白名称 | Tripartite motif-containing protein 29 |
| Uniprot ID | |
| 功能 | It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line. |
| 分子量 | Theoretical: 66 kDa. Actual: 68 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |