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IgE Fc Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P01854-1.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 496 | 6-8日内发货 | |
| 10 μg | ¥ 791 | 6-8日内发货 | |
| 20 μg | ¥ 1,330 | 5日内发货 | |
| 50 μg | ¥ 2,650 | 5日内发货 | |
| 100 μg | ¥ 4,470 | 5日内发货 | |
| 200 μg | ¥ 7,360 | 5日内发货 | |
| 500 μg | ¥ 14,170 | 5日内发货 |
| 生物活性 | Immobilized Human Fc epsilon RI alpha, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human IgE, His Tag with the EC50 of 2.5 ng/ml determined by ELISA. (QC Test) Immobilized Human IgE, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Omalizumab, hFc Tag with the EC50 of 5.0 ng/ml determined by ELISA. |
| 产品描述 | IgE Fc Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P01854-1. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | P01854-1 |
| 蛋白构建 | Ser106-Lys428 |
| 蛋白纯度 | > 95% as determined by Bis-Tris PAGE;
> 95% as determined by HPLC |
| 分子量 | 37.49 kDa (Predicted); 45-60 kDa (Due to glycosylation) |
| 内毒素 | < 0.1 EU/μg of the protein as determined by the LAL method. |
| 蛋白性状 | Solution |
| 缓冲液 | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule. |