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别名 迪扎米珠单抗, GSK2398852, GSK 2398852, Anti-Serum Amyloid P/SAP Reference Antibody (Dezamizumab)
Dezamizumab(GSK 2398852)是一种全人源化重组单克隆免疫球蛋白G1 (IgG1) 抗体,特异性靶向血清淀粉样P成分 (SAP)——一种普遍存在于所有类型淀粉样沉积物中的蛋白质。Dezamizumab抗体通过触发免疫治疗机制,借助巨噬细胞介导的吞噬作用清除淀粉样纤维。可应用于淀粉样轻链 (AL) 淀粉样变性及其他系统性淀粉样疾病的研究。
Dezamizumab(GSK 2398852)是一种全人源化重组单克隆免疫球蛋白G1 (IgG1) 抗体,特异性靶向血清淀粉样P成分 (SAP)——一种普遍存在于所有类型淀粉样沉积物中的蛋白质。Dezamizumab抗体通过触发免疫治疗机制,借助巨噬细胞介导的吞噬作用清除淀粉样纤维。可应用于淀粉样轻链 (AL) 淀粉样变性及其他系统性淀粉样疾病的研究。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 2,320 | 现货 | |
| 5 mg | ¥ 5,490 | 现货 | |
| 10 mg | ¥ 7,480 | 现货 | |
| 25 mg | ¥ 10,900 | 现货 |
| 产品描述 | Dezamizumab (GSK 2398852) is a fully humanized recombinant monoclonal immunoglobulin G1 (IgG1) antibody specifically targeting the serum amyloid P component (SAP), a protein universally found in all types of amyloid deposits, and it possesses potential anti-amyloid activity by triggering an immunotherapeutic mechanism for the clearance of amyloid fibrils through macrophage-mediated phagocytosis, which can be applied in the research of amyloid light-chain (AL) amyloidosis and other systemic amyloid diseases. |
| 别名 | 迪扎米珠单抗, GSK2398852, GSK 2398852, Anti-Serum Amyloid P/SAP Reference Antibody (Dezamizumab) |
| 反应种属 | Human |
| 应用 | ELISA FCM Functional assay |
| 抗体种类 | Monoclonal |
| 内毒素 | <1.0 EU/mg |
| 同型 | Human IgG1 kappa |
| 推荐同型对照 |
| 偶联 | Unconjugated |
| 基因ID | |
| Uniprot ID | |
| 靶点 | Serum Amyloid P/SAP |
| 分子量 | 145.82 kDa |
| CAS No. | 1662664-56-3 |
| 存储 | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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