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G-CSF Protein, Human, Recombinant (Isoform 2) V2

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产品编号 TMPY-04829U

G-CSF Protein, Human, Recombinant (Isoform 2) is expressed in E. coli. The accession number is P09919-2.

G-CSF Protein, Human, Recombinant (Isoform 2) V2

一键复制产品信息

产品编号 TMPY-04829U

G-CSF Protein, Human, Recombinant (Isoform 2) is expressed in E. coli. The accession number is P09919-2.

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产品信息

生物活性	Measured in a cell proliferation assay using NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.03 ng/ml(Regularly tested).
产品描述	G-CSF Protein, Human, Recombinant (Isoform 2) is expressed in E. coli. The accession number is P09919-2.
种属	Human
表达系统	E. coli
蛋白编号	P09919-2
别名	集落刺激因子,G-CSF,GCSF,CSF3OS,colony stimulating factor 3 (granulocyte),C17orf33OS,C17orf33
蛋白构建	Thr31-Pro204
蛋白纯度	> 95% as determined by SDS-PAGE
分子量	18.8 kDa (Predicted); 16 kDa (Reducing conditions)
内毒素	< 0.01 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150 mM NaCl, 0.004% Tween 80, 5% Mannitol, pH 4.0.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, Interleukin-1, and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by Interleukin-17.