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Anti-TRIB3 Antibody (9I365) 是一种 Rabbit 抗体,靶向 TRIB3。Anti-TRIB3 Antibody (9I365) 可用于 WB,IP。
Anti-TRIB3 Antibody (9I365) 是一种 Rabbit 抗体,靶向 TRIB3。Anti-TRIB3 Antibody (9I365) 可用于 WB,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-TRIB3 Antibody (9I365) is a Rabbit antibody targeting TRIB3. Anti-TRIB3 Antibody (9I365) can be used in WB,IP. |
| Ig Type | IgG |
| 克隆号 | 9I365 |
| 反应种属 | Human |
| 应用 | WBIP |
| 推荐剂量 | WB: 1:500-2000; IP: 1:20-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Highest expression in liver, pancreas, peripheral blood leukocytes and bone marrow. Also highly expressed in a number of primary lung, colon and breast tumors. Expressed in spleen, thymus, and prostate and is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, and kidney. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Inactive protein kinase which acts as a regulator of the integrated stress response (ISR), a process for adaptation to various stress.Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. |
| 免疫原 | A synthesized peptide: human TRIB3 |
| 抗原种属 | Human |
| 基因名称 | TRIB3 |
| 基因ID | |
| 蛋白名称 | Tribbles homolog 3 |
| Uniprot ID | |
| 功能 | Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. |
| 分子量 | Theoretical: 40 kDa. Actual: 40 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |