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Anti-Stromal interaction molecule 1 Antibody (8X722)

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货号 TMAB-13248

Anti-Stromal interaction molecule 1 Antibody (8X722) 是一种 Rabbit 抗体，靶向 Stromal interaction molecule 1。Anti-Stromal interaction molecule 1 Antibody (8X722) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

Anti-Stromal interaction molecule 1 Antibody (8X722)

Anti-Stromal interaction molecule 1 Antibody (8X722)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13248

Anti-Stromal interaction molecule 1 Antibody (8X722) 是一种 Rabbit 抗体，靶向 Stromal interaction molecule 1。Anti-Stromal interaction molecule 1 Antibody (8X722) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Stromal interaction molecule 1 Antibody (8X722) is a Rabbit antibody targeting Stromal interaction molecule 1. Anti-Stromal interaction molecule 1 Antibody (8X722) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Ig Type
IgG
克隆号
8X722
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIPIF
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IP: 1:20-50; IF: 1:100-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Endoplasmic reticulum membrane. Cytoplasm > cytoskeleton. Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium. Associated with the microtubule network at the growing distal tip of microtubules. Tissue Specificity : Ubiquitously expressed in various human primary cells and tumor cell lines.
组织特异性Ubiquitously expressed in various human primary cells and tumor cell lines.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景STIM1 is a potential tumor suppressor; defects in STIM1 may cause rhabdomyosarcoma and rhabdoid tumors. STIM1 can either homodimerize or form heterodimers with STIM2. STIM2 possesses a high sequence identity to STIM1 and can function as an inhibitor of STIM1-mediated plasma membrane store-operated Ca2+ entry. However, further investigation is required to elucidate the true physiological function of STIM2.
抗原信息
免疫原
A synthesized peptide: human Stromal interaction molecule 1
抗原种属
Human
基因名称
STIM1
基因ID
6786
蛋白名称
Stromal interaction molecule 1
Uniprot ID
Q13586
功能
Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
化学信息
分子量Theoretical: 77 kDa. Actual: 77 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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